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All other studies have been conducted in animal/rodent models with the vast majority exploring gastrointestinal benefits

Advanced formulations for intranasal delivery of biologics

This includes patients receiving intramuscular injections (typically 1,000 micrograms) for pernicious anaemia or documented B12 deficiency, as well as individuals taking high-dose oral supplements exceeding the Reference Nutrient Intake (1

Copper compounds are also used as actives or excipients in cosmetic and pharmaceutical products, e.g., copper peptide for skin regeneration purposes, cupric aspirinate and cupric salicylate for rheumatoid arthritis treatment, copper conjugated dendrimer for anti-tumoral activity, and copper liposome for enhanced stability of doxorubicin 5,6,7,8,9

If you go any deeper than this, you risk tapping a nerve or artery

J Clin Investig 2015