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Apply evenly across the face and neck

So, you would have already purified proteins corresponding to the full-length and each individual domain of the interacting protein, and now you do a pull-down to see which ones bind

An October 2016 article in the Journal of Chemical Education points out there is commercially available hydrogen chloride (HCl) with a pH of -1.1, sodium hydroxide (NaOH) with a pH of 15, and even hot springs around Russias Ebeko Volo with a pH of -1.7