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Patients switch because of efficacy, tolerability, access, cost, insurance coverage, or newer options becoming available

Across studies, fat mass decline predominated, whereas reductions in lean body mass were modest
In an attempt to compensate for the loss, other pathways are upregulated, e.g., the increased use of ketones produced from fatty acids by astrocytes that are shuttled to neurons

Serena Williams was one of the many celebrities featured in a Super Bowl ad, but she may have received the most backlash.

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The GLP-1 Revolution: The Companies Dominating One of Pharma's Fastest-Growing Markets The global GLP-1 market has transformed from a niche diabetes segment into one of the most valuable therapeutic categories in pharmaceutical history
