glutathione and metalothionein Mechanisms of microbial bioremediation of heavy metals. GSH, Box plots of expression level

The primary response of plants to metal stress is the generation of reactive oxygen species (ROS) such as superoxide (O 2 ), hydrogen peroxide (H 2 O 2 ) and the hydroxyl radical (HO ), the major contributors to oxidative damage [95,96]

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Another significant Nrf2 target gene is HO-1 provides defence against oxidative damage and has outstanding antioxidant qualities 39