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PMC 11593403

It contributes to energy production by supporting the metabolism of fatty acids and the synthesis of acetyl-coenzyme A, the central substrate for energy production that also helps maintain homeostasis between catabolic and anabolic reactions

doi: 10.3389/fphar.2023.1182788 Received 09 March 2023 Accepted 31 March 2023 Published 06 April 2023 Volume 14 - 2023 Edited by Xuelin Zhou, Capital Medical University, China Reviewed by Yachen Shen, University of Pennsylvania, United States Yusheng Li, University of Mississippi, United States Shengjie Xu, Merck, United States Changlu Xu, University of California, Los Angeles, United States Updates Copyright 2023 Jing, Iba, Naito, Xu, Morishige, Nagata, Okubo and Ando

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During this process excess of the cytosolic end product of glycolysis, pyruvate, is converted into lactate and secreted into the extracellular environment (the so-called Warburg effect) 1,2

PMID: 19043625