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The results showed that DHM promoted the expression of autophagy-related proteins (Beclin1, VPS34, CTSD, and LC3II), inhibited oxidative stress and pyroptosisin H2O2-induced BV-2 cells

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Both in vivo and in vitro experiments show IGF-2 activates the IGF-1R/PI3K/AKT pathway, reducing apoptosis and inflammation
Reduced function of GPX4 is frequently observed in degenerative disorders
