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Description
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Patients may also show growth impairment, psoriasiform lesions (well-defined scaly plaques most often found on the elbows) and frequent infections [1]
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Dysfunctional mitochondria release into the cytoplasm, it binds to with Apaf-1, triggering caspase-9, caspase-3 related cascade reactions that lead to apoptosis (Santucci et al., 2019

May 2018;45(5):413-421

while cisplatin-induced phosphorylation of BAD Ser- 136 is PI-3K-Akt-dependent