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(2014) developed a refined graded nerve injury and von Frey assessment approach to quantify sex differences in mechanical allodynia, revealing exaggerated and hormone-dependent tactile hypersensitivity in female rats across estrous phases (Nicotra et al., 2014)

mechanistic) target of rapamycin complex 1 (mTORC1) and the AMP-activated protein kinase (AMPK)

Furthermore, there is a transition of mouse de novo methyltransferase expression from Dnmt3b to Dnmt3a during neural progenitor cell development [50], suggesting that particular DNMTs play a role in neuronal function at specific times over neuronal development and maturation

For example, the researchers conducted experiments with cartilage cells and noted that FOXO4-DRI [may] remove the senescent cells in PDL9 chondrocytes

H., Yoon, J

doi: 10.3389/fnut.2023.1239838 136