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[DOI] [PMC free article] [PubMed] [Google Scholar] Ma, Z

Neurology 50 , 17551760 (1998)

According to a 2020 review, people who consume a diet thats low in lutein and zeaxanthin may be at a higher risk of developing cataracts

Additionally, the inhibition of mitophagy may also reduce the expression of antioxidant enzymes [62]

(10) Also excluded were those who had received liver function-enhancing medications, antibiotics, choleretic agents, antioxidants, or dietary supplements within 14 days of the first dose of the investigational product, or who did not agree to abstain from such medications from 14 days to the end of the study, (11) and those who had received drugs that induce or inhibit drug metabolizing enzymes, such as barbiturates, within 30 days of the first dose of the investigational product, or who did not agree to abstain from such drugs from 30 days to the end of the study

Given that lens opacity is a direct result of oxidative stress, the concentrations of these antioxidants are frequently used as markers of cataract formation, both clinically and in animal models (1,2)