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Muscle mass: Preserving muscle mass during GLP-1 mediated weight loss requires deliberate attention to protein intake and resistance training

It is known that the insulin resistance (i.e., the insensitivity of cells, in particular, hepatocytes, skeletal muscle cells, and adipocytes to insulin, the primary hormone in glucose homeostasis in the fed state) predisposes to T2DM

10.1371/journal.pone.0174839 112 YangW.XiaY.CaoY.ZhengY.BuW.ZhangL.et al (2012)

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Enhanced Fat Loss Growth hormone also plays a role in fat metabolism