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Severe liver dysfunction, as the liver plays a key role in metabolizing lipotropic compounds

L-Carnitine and Heart Disease
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Goetz CG, Stebbins GT, Chung KA, Nicholas AP, Hauser RA, Merkitch D, Stacy MA

The increased levels of the circulating diol enhance fatty acid uptake in BAT, which is involved in heat production in adults, and reduce levels of serum triglycerides
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