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Unlike pharmaceutical agents (e.g., statins) that carry side effects (e.g., myopathy), probiotics are generally safe and exert pleiotropic effects, including cholesterol lowering, anti-inflammation, and endothelial protection ( 2 PRISMA compliance and literature selection process 3 Gut microbiota dysbiosis and atherosclerosis: the mechanistic link Gut microbiota dysbiosis contributes to AS through three interconnected pathways: metabolic dysregulation, inflammatory activation, and vascular dysfunction ( Figure 1 )

Folate receptor autoimmunity and cerebral folate deficiency in low-functioning autism with neurological deficits

11 Another trial evaluated a cream containing modified glutathione (0.1% GSH-C4), 0.5% beta-glycyrrhetic acid, and 10% azelaic acid in patients with mild-to-moderate rosacea, showing a reduction in inflammatory papules at Week 8

Many children with ASD also have sensorimotor impairments, which can affect their performance in academic settings, and this can be modulated by occupational therapy (OT) to significantly augment sensory processing and refine motor difficulties to increase functionality and independent daily living skills

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Nitric oxide system modulation