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In our translational work, we also reported a link between LAC levels, cellular aging and metabolic function in the antidepressant responses to the insulin-sensitizing agent pioglitazone, an agent for treatment of diabetes type 2 and tested as potential antidepressant [60]

Perhaps the closest thing to a long-term cure that exists is a prescription drug called isotretinoin (often referred to by its former brand name, Accutane)


doi: 10.1002/jnr.20386


Reversal of cross-linking was performed by incubating samples overnight at 65C
