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This study reports that there were no side effects in either populations [28]

The evidence base is overwhelmingly preclinical, and there are no completed, published Phase 2 or 3 human efficacy trials only early-stage safety work [9]

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The clinical trials showed steady weight loss progression through 68 weeks, with the most rapid loss occurring between weeks 8 and 32

Effective and efficient rehab is criterion-based, not time-based

In patients with Parkinsons disease on levodopa monotherapy, vitamin B supplementation can increase peripheral levodopa metabolism and thus reduce the amount of levodopa reaching the central nervous system, worsening symptom control