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Bremelanotide Prescribing Information

Available: arXiv:1308.0850v5 ^ Graves et al

pmid:14622602

Hulme H, Meikle LM, Strittmatter N, van der Hooft JJJ, Swales J, Bragg RA, et al

Recent findings highlight a dysregulation characterized by a T-helper 1 (Th1)/T-helper 2 (Th2) imbalance, which promotes abnormal immune responses, ultimately contributing to the disease pathology [54]

Biguanides A double-blinded randomized controlled trial (RCT) assessing the efficacy of metformin in the prevention of PIPN showed that the development of grade two or more peripheral neuropathy (PN) was significantly lower in the metformin group compared to placebo ( p = 0.001)
