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Mechanistic studies have demonstrated that 5(S),15(S)-DiHETE-mediated ferroptosis signalling facilitates the degradation of hypoxia-inducible factor-1 (HIF1)

After DSS induction, the mice showed, decreased body weight and increased colon damage, intestinal dysbiosis, myeloperoxidase activity in the colon tissues
(2007) 143:932939.e1

J Chem Phys 120:63636374
Targeting the reader of m6A: IGF2BP and YTH domain family The discovery of m6A readers with specific motifs has spurred significant interest in developing drugs targeting these proteins, expanding the possibilities for therapeutic interventions
