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Bae, J.-H., Song, D.-K

10.1016/j.drudis.2021.06.011 128 TbiT.VcseiL.YoudimM

These NRF2-high TAMs stabilized an EMT phenotype in malignant cells and promoted treatment resistance [19]

Gulley noted

Additional Synergistic Nutrients Other compounds, such as alpha-lipoic acid, N-acetylcysteine, and zinc, are often included in antioxidant therapies to maximize efficacy

The STAT3 factors induce the expression of SOCS proteins which consequently inhibit the function of JAK/STAT3 signaling, i.e., SOCS proteins exert a negative feedback on the JAK/STAT3 signaling induced by both insulin/IGF-1 and certain cytokine pathways
