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B12 is not a stimulant and does not cause jitters or anxiety like caffeine

Conversely, the M2 phenotype supports tissue repair and synaptic remodeling following the pro-inflammatory phase through the secretion of anti-inflammatory cytokines [i.e., IL-10 and transforming growth factor-beta (TGF-)]

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doi: 10.17756/jfcn.2017-045 30