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However, the inhalation of salbutamol in doses recommended by the manufacturer is most likely to result in urinary levels of salbutamol exceeding the urinary threshold of 1,000 ng/ml and thus, the use of salbutamol with a nebulizer requires a TUE

Having a summary understanding of how they arrive at their numbers is relatively important

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When a patient asks about DSIP for sleep, the responsible answer is some version of: the evidence is genuinely weak, so let's make sure we've exhausted the validated approaches first