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UK pharmacy and clinical practice, guided by the Specialist Pharmacy Service (SPS), generally discourages the routine use of multi-dose vials and requires that any in-use shelf life and storage conditions follow validated, product-specific data

[DOI] [PubMed] [Google Scholar] 52.Deamer D, Bangham AD

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[DOI] [PubMed] [Google Scholar] 48.Birk J., Meyer M., Aller I., Hansen H.G., Odermatt A., Dick T.P., Meyer A.J., Appenzeller-Herzog C

Thus, the toxic molecules can re-circulate between the bile and the hepatocytes, causing further depletion of GSH stores

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