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Using lipid nanoparticle-encapsulated siRNA to target and silence macrophage Cxcl2 markedly reduces myocardial neutrophil infiltration, diminishes inflammation, and reduces infarct size, concurrently demonstrating that aberrant macrophage chemotactic activity is a key target exacerbating post-inflammatory myocardial ischemic injury (33)

The as-synthesized carbon dots were used for photothermal therapy and multiphoton therapy

Khater School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran Sorour Khateri Global Consortium for Public Health Research, Datta Meghe Institute of Higher Education and Research, Wardha, India Mahalaqua Nazli Khatib Department of Neurosurgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran Hamid Reza Khayat Kashani Brain and Spinal Cord Injury Research Center, Tehran University of Medical Sciences, Tehran, Iran Zahra Khazaeipour Department of Epidemiology, Shahroud University of Medical Sciences, Shahroud, Iran Ahmad Khosravi Department of Public Health, New Mexico State University, Las Cruces, NM, USA Jagdish Khubchandani Institute of Health Services Research, Yonsei University, Seoul, South Korea Gyu Ri Kim, Doo Woong Lee & Eun-Cheol Park Department of Preventive Medicine, Korea University, Seoul, South Korea Jihee Kim & Yo Han Lee School of Traditional Chinese Medicine, Xiamen University Malaysia, Sepang, Malaysia Yun Jin Kim Department of Nutrition, Simmons University, Boston, MA, USA Ruth W

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Both institutions are supporting research and the generation of organoids as models of human diseases

Additionally, BP1003 effectively disrupts the polarization of monocytes into M2 macrophages, which are typically associated with creating a pro-tumorigenic environment by suppressing immune responses