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In all, persistent tissue injury provokes chronic inflammation and an increase of pro-fibrotic factors, such as TGF-1, ROS, PAI-1, ROCK, TNF, and TIMPs, which induce the phenotype transformation of precursor cells to myofibroblasts
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2018;3:e419e428
Summary updated in July 2014 by Peter Renner and Markus Horneber
doi: 10.1002/elps.200900692
