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This, in turn, results in the upregulation of SLC38A2 expression, the enhancement of glutamine uptake and depletion of glutamine from natural killer (NK) cells, and the promotion of immune escape [127]

Ren H, Hu B, Jiang G

Drug Administration and Experimental Design All drugs were dissolved in saline (SAL)

Additional support for the model of GST regulation is provided by the observations that either immunodepletion of GST , or its inhibition by a rationally designed GSH-based-peptidomimetic inhibitor, - -glutamyl- S -(benzyl)cysteinyl- R ()-phenyl glycine diethyl ester (TLK199), also results in the activation of JNK

However, its unavailability or lack of sensitivity poses limitations

& Gambillara, V