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Oral glutathione has limited intestinal absorptiontypically 515%meaning much of the dose may not reach systemic circulation

Glutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosis

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[DOI] [PubMed] [Google Scholar] 79.Nassir F., Rector R.S., Hammoud G.M., Ibdah J.A

Selenium deficiency can be caused by intestinal malabsorption or increased loss through diarrhea, which may be symptoms of cancer or can be associated with anti-cancer treatment (including radiotherapy and gastrointestinal surgery) (376, 377)