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Together, these findings suggest that CBS refuels cysteine pools for GSH synthesis through de novo cysteine biosynthesis under cystine restricted conditions

123 SteyfkensF.ZhangZ.Van ZeebroeckG.TheveleinJ

[DOI] [PubMed] [Google Scholar] 173.Peric H., Fraser I.S

It is particularly common in individuals with certain risk factors, including those who have undergone gastric or small intestine resections, have inflammatory bowel disease, use metformin or proton pump inhibitors, follow a vegan diet, or are older than 75 years

A novel assay that measures the GGT hydrolysis reaction at physiological pH and osmolarity has shown that the second order rate kinetics for GSH and glutathione S -conjugates are similar (Wickham et al., 2011)

Funding This work was funded by the National Natural Science Foundation of China (No
