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hydrophila -infected crucian carp, dietary supplementation with GR-6/GR-7 consortium increases survival by 50%, with restored gut microbiota diversity and attenuated systemic inflammation (Alkaline phosphatase, Lysozyme and GSH/GSSG ratio)

Immunosuppressive pathways The microbiota may play a regulatory role in the recruitment and function of Tregs and MDSCs, which are key immunosuppressive players in the TME

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296,297,298 The pivotal function of CXCR1 in resistance to infection was demonstrated in humans harboring a variant of the CXCR1 gene, which correlated with heightened susceptibility to bacterial infections