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Ketika jumlah radikal bebas lebih banyak dalam tubuh dibandingkan antioksidan, terjadi kerusakan sel dalam tubuh

doi: 10.5607/en.2016.25.4.147

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This harsh environment is shaped by the intrinsic metabolic activities of tumor cells, stromal remodeling, inflammatory signaling, and the physical characteristics of the lung tissue itself, such as high oxygen demand and exposure to inhaled toxins

The Val158Met polymorphism in COMT gene and cancer risk: Role of endogenous and exogenous catechols