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Uric acid activates the NF-B signaling pathway by stimulating NLRP3 inflammasome

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Rhein protects against acetaminophen-induced hepatic and renal toxicity

The 2% and 5% topical formulations require no prescription, though higher concentrations or oral formulations fall under different regulatory categories

This increases CD8 + T cell infiltration and enhances the sensitivity of triple-negative breast cancer (TNBC) to anti-PD-1 therapy (340)

Clinical samples and datasets were analyzed and in vitro and in vivo experiments were performed to confirm the critical function of METTL14 in CDK4/6i resistance