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methodology, S.A., G.F.S
Cancers growing in a lipid-rich niche display enhanced lipid utilization, providing survival advantages for cancer cells [64, 65]

doi: 10.1038/ncomms7498

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Jin JL, Guo YL, Li JJ

Research has confirmed that the Nle4 and D-Phe7 substitutions in MT-1 produce substantially extended in vitro and in vivo stability relative to native -MSH , documenting resistance to endopeptidase cleavage at the position 7 Phe bond and prevention of methionine oxidation that inactivates native -MSH, resulting in prolonged receptor occupancy and sustained downstream signalling