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"Association of Vitamin B12 Deficiency with Homozygosity of the TT MTHFR C677T Genotype, Hyperhomocysteinemia, and Endothelial Cell Dysfunction"

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Because its beta subunit binds to the exact same transmembrane LH/CG receptors found on target cells, researchers utilize it to bypass standard hypothalamic-pituitary-gonadal (HPG) axis signaling and directly observe downstream cellular responses
