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Available in dairy products and supplements

Pulm Pharmacol Ther 21(2):247258

Epigenetics is a heritable intricate mix of pathobiological and environmental factors which impinge upon disease development and/or resolution without any changes taking place in the organismal DNA (121)

Although the effects of systemically administered hydroxychloroquine have not been evaluated in any AAV gene therapy studies, it is likely that hydroxychloroquine would need to be administered in the weeks prior to AAV delivery to allow hydroxychloroquine to reach appropriate tissue concentrations within the eye