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A risk of bias (RoB) assessment of studies was completed using the Cochrane RoB tool as well as the JBI critical appraisal checklist

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doi: 10.3390/nu8090579

The primary role of ICL is to catalyze conversion of isocitrate to succinate and glyoxylate to maintain energy generation and gluconeogenesis during growth on fatty acids

Nature 336 : 783787

5-Amino-1MQ works by inhibiting NNMT (nicotinamide N-methyltransferase), an enzyme that depletes cellular NAD+ and SAM
