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[6] [7] At millimolar concentrations, they may also modulate the redox state of the NMDA receptor complex

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340 Therapeutic leverage of ROS elevation in cancer treatment Since the 1950s, various strategies/drug research have been implemented based on this concept, such as administering ROS or ROS-generating enzymes to tumor cell lines or murine models with tumors

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Even though it may have been a more common phenotype at one point in time, other environmental variables could result in a shift in the percentage distribution year over year

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Publ.,1991171 EOF86 EOF 70

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J Am Chem Soc 141:2040720415 Hassannia B, Wiernicki B, Ingold I, Qu F, Van Herck S, Tyurina YY, Bayir H, Abhari BA, Angeli JPF, Choi SM et al (2018) Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

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Like any other organ, the brain is vascularized from the surrounding vascular plexus during embryogenesis, and the BBB is tempered by the bodys immune system from embryonic development [513]

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