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Elevated CNS levels of HGF have been measured in patients diagnosed with multiple sclerosis, Parkinsons disease, amyotrophic lateral sclerosis and spinal cord injury [91-94]

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This triggers the respiratory burst by generating superoxide anions (O 2 ) [61, 62], which are subsequently converted to hydrogen peroxide (H 2 O 2 ), hydroxyl radicals (OH ), and hypochlorous acid

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144 MESH1 also modulates ferroptosis by controlling the degradation of NADPH, a central metabolite in redox homeostasis
