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Inhibition of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) NOX is a plasma membrane-bound enzymatic complex that catalyzes the production of superoxide from oxygen and NADPH and has been involved in innate immune defense against microbes (39)

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In contrast, no such translocation could be detected in morphine-treated cells which produce a PKC-dependent MOR desensitization