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In summary, the presence of macrophages in the TC models resulted in an earlier and more pronounced inflammation, lipid alteration and EMT response to CS exposure, highlighting the critical role of these cell types in mediating the cellular response to CS exposure
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Folic acid supplementation up-regulated SLC7A11 expression, then restored GSH biosynthesis and antioxidant enzyme activity of GPX 4 , thereby attenuating brain tissue and intraneuronal iron overload, the accumulation of free radicals, and toxic lipid peroxidation

The machine-learning-mediated interface of microbiome and genetic risk stratification in neuroblastoma reveals molecular pathways related to patient survival
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These are general observations, not guaranteed outcomes