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Definitive measurements on the uptake or otherwise of ERG into isolated mitochondria, or indeed into other organisms that cannot make it, are eagerly awaited

doi: 10.1073/pnas.1014480108 180 Lucio-EterovicAKPiaoYde GrootJF

Under normal conditions, these molecules play physiological roles in cellular signaling, immune defense, and wound healing

In HM3KO melanoma cells, nilotinib was found to upregulate MITF and its downstream genes by activation of the cAMP/PKA/CREB signaling pathway and decreasing the phosphorylation of AKT, which repressed the pigmentation process by inhibition of GSK3 179

M., Brennan K

Appl Sci 11(9):4305