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[DOI] [PubMed] [Google Scholar] 38.Ferreira MC, Witz CA, Hammes LS, et al
Figure 2 2.2.2.2 BL regulates adaptive immunity in PD Postmortem analyses of PD patients and animal models consistently reveal significant blood-brain barrier disruption, accompanied by enhanced peripheral immune cell migration and prominent T cell infiltration (predominantly CD3 + , CD4 + , and CD8 + subsets) within the substantia nigra ( + T cell populations are reduced, whereas the suppressive activity of CD4 + FOXP3 + Tregs is augmented ( + T cells in PD patients specifically recognize -Syn epitopes, triggering FAS receptor-mediated apoptotic signaling and increased secretion of inflammatory mediators, including IL-10
doi: 10.2147/COPD.S374670

Coffee is an amazing substance, and research shows that coffee drinkers are less likely to have dementia, Parkinsons disease, type 2 diabetes, strokes, and certain types of cancers

Although limited, there are also published studies that focus on Asian populations
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[PubMed] [Google Scholar] Schubert F., Khn S., Gallinat J., Mekle R., Ittermann B
