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While TTR-V30M carriers in the Portuguese, Brazilian, and Japanese populations share a common ancestral origin, the same mutation in Sweden has arisen independently [8]
Redox homeostasis ensures that cells respond to these redox stressors efficiently

SAA are used to replenish the stores of GSH, which can be considered a storage form for sulfur, and only when this goal is met is the excess oxidized to sulfate
Beyond sourcing, proper handling is the other major pitfall

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Astrocyte-neuron interactions have been suggested to be crucial for neuronal survival [74,75]
