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doi: 10.1016/j.fochms.2022.100133 15 KannoTNakajimaTMiyakoKEndoY

Constant follow-up and lifelong mineral and multivitamin supplementation are recommended [5,53,133]

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-/- homozygotes also present with some loss of function in cerebral vessels and abnormal lipid deposition in the aorta and disruption of the laminar structure of the cerebellum with no obvious changes in the cortex or cerebrum ( Unlike MTHFR and CBS knockout mice, dietary induction of HHcy allows for age related HHcy to be studied

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