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223 Dynamin-related protein 1 promotes fragmented mitochondrial puncta formation in latent brain metastatic cells, leading to a shift towards fatty acid oxidation (FAO) metabolism that maintains redox homeostasis and survival of tumor cells within the brain microenvironment

In addition, different factors that hinder the uptake of neuro-therapeutics to treat life-threatening-brain diseases of CNS are described

J Pharmacol Exp Ther 2006

2014;2:91 Peagarikano O, Lzaro MT, Lu X-H, Gordon A, Dong H, Lam HA, et al

mEPSCs were recorded form mRFP -actin transfected hippocampal neurons treated for 5 days with Hinge (10 "12 M), HGF (10 ng/ml), Dihexa (10 "12 M), Hinge + HGF (10 "S 2 M + 10 ng/ml, respectively) or Hinge + Dihexa (10 "12 M each)
