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Even under normal levels of glutamate, mitochondrial dysfunction will increase the susceptibility of nigral neurons to glutamate excitotoxicity effects (85)

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Tolerogenic nanoparticles restore the antitumor activity of recombinant immunotoxins by mitigating immunogenicity

Fc-Galactosylation of human immunoglobulin gamma isotypes improves C1q binding and enhances complement-dependent cytotoxicity

Both patterns appear in the research framing
