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Additional exploratory endpoints for which data are not reported were: permanent discontinuation of trial product between baseline and week 104

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Low dose long-term corticosteroid therapy in rheumatoid arthritis: An analysis of serious adverse events

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The key hormonal imbalances associated with PCOS include: Elevated androgen levels PCOS is characterized by an excess production of male hormones, such as testosterone

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However, the studys limitations include the small number of available RCTs for tirzepatide and the lack of data on varying dosages

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Maladaptive behaviour patterns of cycling, such as a greater number of past weight loss attempts, weight gain, a greater desire to lose weight, and even weight maintenance, can represent a significant psychological issue, as they have been shown to be associated with an increased risk of depression and anxiety [177]

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