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Specifically, cells derived from tumors treated with the Palbociclib and Telaglenastat combination presented a general decrease in central carbon metabolic fluxes in conjunction with an overall reduction in mitochondrial respiration, as well as in mitochondrial, glycolytic, and total ATP production

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The pattern is unmistakable: AI is no longer a peripheral tool in drug discovery it is becoming the core infrastructure around which the next generation of biopharma pipelines will be built

and is both neuroprotective and cardioprotective (Seeds, 2020)