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Bancroft JD, Gamble M

The most dominant limitation is considerable variation in the absorption and action of drug from patient to patient, but more importantly from injection to injection for the same patient 10,11,12,13

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Additionally, the synthesis of LDL receptors increases to allow increased cholesterol uptake for bile acid synthesis, and the overall effect is a reduction in plasma cholesterol

Metformin, a popular diabetes drug, has also been studied for its ability to reduce thyroid nodules through its blood-sugar regulating properties, but I prefer to use berberine, as it has fewer potential side effects