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While some people may experience a boost in energy within a few days, its important to remember that B12 deficiency can be a complex issue

[DOI] [PMC free article] [PubMed] [Google Scholar] Pearson WR, Lipman DJ

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Rather than waiting until you feel depleted, the goal should be to maintain a steady baseline of support

Miele L, Grieco A, Armuzzi A, Candelli M, Forgione A, Gasbarrini A, Gasbarrini G (2003) Hepatic mitochondrial beta-oxidation in patients with nonalcoholic steatohepatitis assessed by 13C-octanoate breath test