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& Sun, Y

Abstract Calcium oxalate (CaOx) is the most common type of kidney stone, and its crystal deposition can induce oxidative stress, inflammatory responses, and cell death

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Accessed May 2023 at

doi:10.5607/en.2019.28.4.495 63

Thus, with such a background (i.e., useful modulation/control of the increased angiogenesis, elevated VEGF levels, upregulation of the egr-1 gene, enhanced NO and eNOS stimulation, and counteraction of increased free radical formation), stable gastric pentadecapeptide BPC 157 is working as a cytoprotective agent (and, therefore, with a highly postulated safety profile) (and not as a panacea effective for all conditions)