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10.4049/jimmunol.180.1.618 131 JakusZ.SimonE.FrommholdD.SperandioM.MocsaiA

The levels of glutathione depend on the mutation in question, and nrc1 , cad2-1 , pad2-1 and zir1 , which are affected in GSH1 show glutathione levels that range from 45 to 15% of normal levels 50,51,54,68

Ultimately, these series of reactions will activate the apoptotic pathways 33,34 (Figure 4)

Then, rats were anesthetized by diazepam (2.5 mg/kg i.p., Sigma, USA) and ketamine (50 mg/kg i.p., Sigma, USA) and heart tissues were collected for left ventricular papillary muscle contractile assessment, oxidative stress markers analysis, and histopathological studies

eBioMedicine 78, 103968