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L-carnitine alters lipid body content in pre-implantation embryos leading to infertility

Similarly, CUMS models show reduced mitochondrial membrane potential, impaired ATP production, decreased PINK1 and Parkin expression, alongside increased mtROS, p62, and apoptosis-associated speck-like protein containing CARD (ASC)

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Using a novel highly sensitive mass spectrometry approach based on Surface-Activated Chemical Ionization (SACI) with an Electrospray Ionization (ESI) source and bioinformatics analyses (SANIST platform) for biomarker discovery, we had found that 3 molecules from the carnitine family were significantly decreased in serum sample from PCa patients, as compared to controls [16]

These symptoms prompted Sommers team to examine skin biopsies for changes in the small nerves conveying tactile sensations