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All bonds were constrained using the SHAKE algorithm, and the integration step was set to 1 fs employing the Verlet leapfrog algorithm

Analysis can be undertaken from mtDNA extracted from blood, skin biopsy, or muscle

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To emphasize the non-neoplastic nature of the disease, Tomich and Zunt suggested the term melanoacanthosis while reserving the designation "melanoacanthoma" for cutaneous tumors

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